Human Pathology
Volume 34, Issue 1 , Pages 92-95 , January 2003

Fatal parvovirus B19–associated myocarditis clinically mimicking ischemic heart disease: An endothelial cell–mediated disease

References 

  1. Murry CE, Jerome KR, Reichenbach DD. Fatal parvovirus myocarditis in a 5-year-old girl. Hum Pathol. 2001;32:342–345
  2. Chia JK, Jackson B. Myopericarditis due to parvovirus B19 in an adult. Clin Infect Dis. 1996;23:200–201
  3. Orth T, Herr W, Spahn T, et al.  Human parvovirus B19 infection associated with severe acute perimyocarditis in a 34-year-old man. Eur Heart J. 1997;18:524–525
  4. Erdman DD, Durigon EL, Wang QY, et al.  Genetic diversity of human parvovirus B19: Sequence analysis of the VP1/VP2 gene from multiple isolates. J Gen Virol. 1996;77:2767–2774
  5. Smith LM, Sanders JZ, Kaiser RJ, et al.  Fluorescence detection in automated DNA sequence analysis. Nature. 1986;321:674–679
  6. Klingel K, Stephan S, Sauter M, et al.  Pathogenesis of murine enterovirus myocarditis: Virus dissemination and immune cell targets. J Virol. 1996;70:8888–8895
  7. Klingel K, Hohenadl C, Canu A, et al.  Ongoing enterovirus-induced myocarditis is associated with persistent heart muscle infection: Quantitative analysis of virus replication, tissue damage, and inflammation. Proc Natl Acad Sci U S A. 1992;89:314–318
  8. Blundell MC, Beard C, Astell CR. In vitro identification of a B19 parvovirus promoter. Virology. 1987;157:534–538
  9. Brown KE, Anderson SM, Young NS. Erythrocyte P antigen: Cellular receptor for B19 parvovirus. Science. 1993;262:114–117
  10. Liu W, Ittmann M, Liu J, et al.  Human parvovirus B19 in bone marrow from adults with acquired immunodeficiency syndrome: A comparative study using in situ hybridization and immunohistochemistry. Hum Pathol. 1997;28:760–766
  11. Takahashi M, Ito M, Sakamoto F, et al.  Human parvovirus B19 infection: Immunohistochemical and electron microscopic studies of skin lesions. J Cutan Pathol. 1995;22:168–172
  12. Tedder TF, Steeber DA, Chen A, et al.  The selectins: Vascular adhesion molecules. FASEB J. 1995;9:866–873
  13. Ricotta D, Alessandri G, Pollara C, et al.  Adult human heart microvascular endothelial cells are permissive for non-lytic infection by human cytomegalovirus. Cardiovasc Res. 2001;49:440–448
  14. Nigro G, Bastianon V, Colloridi V, et al.  Human parvovirus B19 infection in infancy associated with acute and chronic lymphocytic myocarditis and high cytokine levels: Report of 3 cases and review. Clin Infect Dis. 2000;31:65–69
  15. Dengler TJ, Raftery MJ, Werle M, et al.  Cytomegalovirus infection of vascular cells induces expression of pro-inflammatory adhesion molecules by paracrine action of secreted interleukin-1beta. Transplantation. 2000;69:1160–1168

 B. D. Bültmann and K. Klingel contributed equally to this study and thus share first authorship.

☆☆ Supported in part by grants from the Federal Ministry of Education and Research (Fö 01KS9602) and the Interdisciplinary Center of Clinical Research Tübingen (IZKF) awarded to K.K.

 Address correspondence and reprint requests to Burkhard D. Bültmann, MD, Institute of Pathology, University of Tübingen, Liebermeisterstrasse 8, D-72076 Tübingen, Germany.

PII: S0046-8177(03)00003-0

doi: 10.1053/hupa.2003.48

Human Pathology
Volume 34, Issue 1 , Pages 92-95 , January 2003