Human Pathology
Volume 36, Issue 5 , Pages 571-575 , May 2005

Transformation of follicular lymphoma to Burkitt-like lymphoma within a single lymph node

  • Sanjay Mukhopadhyay, MD

      Affiliations

    • Department of Pathology, State University of New York Upstate Medical University, Syracuse, NY 13210, USA
    • Corresponding Author InformationCorresponding author. Department of Pathology, State University of New York Upstate Medical University, Syracuse, NY 13210, USA.
    • ,
  • Joseph Readling, MD

      Affiliations

    • Department of Hematology-Oncology, United Health Services Hospitals, Johnson City, NY 13210, USA
    • ,
  • Philip D. Cotter, PhD, FACMG

      Affiliations

    • Advanced Molecular Diagnostics, Cytogenetics and Molecular Genetics, US Laboratories, Irvine, CA 92612, USA
    • Dr Cotter is currently at the University of California, San Francisco, Calif.
    • ,
  • Anthony E. Shrimpton, PhD

      Affiliations

    • Department of Pathology, State University of New York Upstate Medical University, Syracuse, NY 13210, USA
    • ,
  • Jagmohan S. Sidhu, MD

      Affiliations

    • Department of Pathology, Wilson Memorial Regional Medical Center, Johnson City, NY 13210, USA

References 

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  2. Bastion Y, Sebban C, Berger F, et al. Incidence, predictive factors, and outcome of lymphoma transformation in follicular lymphoma patients. J. Clin. Oncol. 1997;15:1587–1594
  3. Said J. Transformation to aggressive B-cell lymphoma: morphology, immunophenotype, and molecular characteristics. Appl. Immunohistochem. Mol. Morphol. 2003;11:199–205
  4. Lee JT, Innes DJ, Williams ME. Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma. J. Clin. Invest. 1989;84:1454–1459
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  6. Arcinas M, Heckman CA, Mehew JW, Boxer LM. Molecular mechanisms of transcriptional control of bcl-2 and c-myc in follicular and transformed lymphoma. Cancer Res. 2001;61:5202–5206
  7. Paternoster SF, Brockman SR, McClure RF, Remstein ED, Kurtin PJ, Dewald GW. A new method to extract nuclei from paraffin-embedded tissue to study lymphomas using interphase fluorescence in situ hybridization. Am. J. Pathol. 2002;160:1967–1972
  8. Macpherson N, Lesack D, Klasa R, et al. Small non-cleaved, non-Burkitt's (Burkitt-like) lymphoma: cytogenetics predict outcome and reflect clinical presentation. J. Clin. Oncol. 1999;17:1558–1567
  9. Boonstra R, Bosga-Bouwer A, Mastik M, et al. Identification of chromosomal copy number changes associated with transformation of follicular lymphoma to diffuse large B-cell lymphoma. Hum. Pathol. 2003;34:915–923
  10. Yano T, Jaffe ES, Longo DL, Raffeld M. MYC rearrangements in histologically progressed follicular lymphomas. Blood. 1992;80:758–767
  11. Yano T, van Krieken JH, Magrath IT, Longo DL, Jaffe ES, Raffeld M. Histogenetic correlations between subcategories of small noncleaved cell lymphomas. Blood. 1992;79:1282–1290
  12. Cory S, Vaux DL, Strasser A, et al. Insights from bcl-2 and myc: malignancy involves abrogation of apoptosis as well as sustained proliferation. Cancer Res. 1999;59:1685s–1692s
  13. McDonnell TJ, Korsmeyer SJ. Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18). Nature. 1991;349:254–256
  14. Strasser A, Harris AW, Bath ML, Cory S. Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature. 1990;348:331–333
  15. Thangavelu M, Olopade O, Beckman E, et al. Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q11) or t(8;22)(q24;q11). Genes Chromosomes Cancer. 1990;2:147–158

PII: S0046-8177(05)00005-5

doi: 10.1016/j.humpath.2005.01.004

Human Pathology
Volume 36, Issue 5 , Pages 571-575 , May 2005

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