Human Pathology
Volume 36, Issue 5 , Pages 480-485 , May 2005

Basal cell hyperplasia: an unusual diagnostic dilemma on prostate needle biopsies

  • Gregory A. Hosler, MD, PhD

      Affiliations

    • Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    • ,
  • Jonathan I. Epstein, MD

      Affiliations

    • Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    • Department of Urology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    • Department of Oncology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    • Corresponding Author InformationCorresponding author. Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA.

Received 29 October 2004 ,Accepted 7 February 2005.

References 

  1. Bennett ED, Gardner WA. Embryonal hyperplasia of the prostate. Prostate. 1985;7:411–417
  2. Cleary KR, Choi HY, Ayala AG. Basal cell hyperplasia of the prostate. Am J Clin Pathol. 1983;80:850–854
  3. Rioux-Leclercq NC, Epstein JI. Unusual morphologic patterns of basal cell hyperplasia of the prostate. Am J Surg Pathol. 2003;27:700–702
  4. Yang XJ, Tretiakova MS, Sengupta E, et al. Florid basal cell hyperplasia of the prostate: a histological, ultrastructural, and immunohistochemical analysis. Hum Path. 2003;34:462–470
  5. Epstein JI, Yang XJ. Prostate biopsy interpretation. 3rd ed. Philadelphia (PA): Lippincott Williams & Wilkins.
  6. Thorson P, Swanson PE, Vollmer RT, et al. Basal cell hyperplasia in the peripheral zone of the prostate. Mod Pathol. 2003;16:598–606
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  12. Rioux-Leclercq NC, Epstein JI. Unusual morphologic patterns of basal cell hyperplasia of the prostate. Am J Surg Pathol. 2002;26:237–243
  13. Wojno KJ, Epstein JI. The utility of basal cell-specific anti-cytokeratin antibody (34 beta E12) in the diagnosis of prostate cancer. A review of 228 cases. Am J Surg Pathol. 1995;19:251–260
  14. Hedrick L, Epstein JI. Use of keratin 903 as an adjunct in the diagnosis of prostate carcinoma. Am J Surg Pathol. 1989;13:389–396
  15. Zhou M, Magi-Galluzzi C, Epstein JI. Prostate basal cell lesions can be negative for basal cell keratins: a diagnostic pitfall. Arch Pathol Lab Med [in press].
  16. Yang XJ, Wu CL, Woda BA, et al. Expression of alpha-methylacyl-CoA racemase (P504S) in atypical adenomatous hyperplasia of the prostate. Am J Surg Pathol. 2002;26:921–925
  17. Zhou M, Chinnaiyan AM, Kleer CG, et al. Alpha-methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions. Am J Surg Pathol. 2002;26:926–931

PII: S0046-8177(05)00084-5

doi: 10.1016/j.humpath.2005.02.015

Human Pathology
Volume 36, Issue 5 , Pages 480-485 , May 2005

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