Human Pathology
Volume 36, Issue 5 , Pages 512-521 , May 2005

Identification of germ cells at risk for neoplastic transformation in gonadoblastoma: An immunohistochemical study for OCT3/4 and TSPY

  • Anne-Marie F. Kersemaekers, PhD

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    • Both authors contributed equally to the work.
  • ,
  • Friedemann Honecker, MD

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    • Department of Hematology/Oncology, University of Tübingen, 72076 Tübingen, Germany
    • Both authors contributed equally to the work.
    • Current address: Department of Oncology and Hematology, University Hospital Hamburg Eppendorf, Martinstr. 52, 20246 Hamburg, Germany.
  • ,
  • Hans Stoop, BSc

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
  • ,
  • Martine Cools, MD

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
  • ,
  • Michel Molier, BSc

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    • Current address: Department of Oncology and Hematology, University Hospital Hamburg Eppendorf, Martinstr. 52, 20246 Hamburg, Germany.
  • ,
  • Katja Wolffenbuttel, MD

      Affiliations

    • Department of Pediatric Urology, Sophia Children's Hospital, Erasmus MC-University Medical Center Rotterdam, 3015 GJ Rotterdam, The Netherlands
  • ,
  • Carsten Bokemeyer, MD

      Affiliations

    • Department of Hematology/Oncology, University of Tübingen, 72076 Tübingen, Germany
  • ,
  • Yunmin Li, PhD

      Affiliations

    • Division of Cell and Developmental Genetics, Department of Medicine, VA Medical Center, University of California, San Francisco, CA 94121, USA
  • ,
  • Yun-Fai Chris Lau, PhD

      Affiliations

    • Division of Cell and Developmental Genetics, Department of Medicine, VA Medical Center, University of California, San Francisco, CA 94121, USA
  • ,
  • J. Wolter Oosterhuis, MD, PhD

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
  • ,
  • Leendert H.J. Looijenga, PhD

      Affiliations

    • Department of Pathology, Josephine Nefkens Institute, Daniel den Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author.

Received 1 February 2005 ,Accepted 15 February 2005.

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 This study was financially supported by the Dutch Cancer Society, grant number 2002 2682 (AMK, HS, JWO, LHJL), and the Deutsche Krebshilfe, Dr Mildred Scheel Stiftung (F.H.), and the European Society for Pediatric Endocrinology, ESPE sponsored by Novo Nordisk A/S (MC).

PII: S0046-8177(05)00085-7

doi: 10.1016/j.humpath.2005.02.016

Human Pathology
Volume 36, Issue 5 , Pages 512-521 , May 2005