« Previous
Next »
Human Pathology
Volume 37, Issue 3
, Pages 352-360
, March 2006
Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis
References
- . Idiopathic pulmonary fibrosis: clinical relevance of pathological classification. Am J Respir Crit Care Med. 1998;157:1301–1315
- . Fibroblast immune-effector function. In: Phipps RP editors. Pulmonary fibroblast heterogeneity. Boca Raton: CRC Press; 1992;p. 295–322
- . Transforming growth factor-b1 induces a-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol. 1993;122:103
- . Mechanisms of myofibroblast activity and phenotypic modulation. Exp Cell Res. 1999;250:273–283
- . Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection. Liver. 2002;22:93–101
- Hepatic stellate cells reversibly express alpha-smooth muscle actin during acute hepatic ischaemia. Transplant Proc. 1997;29:2390–2395
- . Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis. Am J Pathol. 1996;148:527–537
- . Significance of early intra-alveolar fibrotic lesions and integrin expression in lung biopsy specimens from patients with idiopathic pulmonary fibrosis. Hum Pathol. 1995;26:53–61
- Fibroblast activation protein: purification, epitope mapping and induction by growth factors. Int J Cancer. 1994;58:385–392
- Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers. Proc Natl Acad Sci U S A. 1994;91:5657–5661
- . Am J Respir Crit Care Med. 2002;165:277–304
- . Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J Biol Chem. 1999;274:36505–36512
- . Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med. 2001;134:136–151
- . Phenotypic and functional features of myofibroblasts in sheep fetal wounds. Differentiation. 1994;56:173–181
- . Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study. Am J Pathol. 1994;145:114–125
- . Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulation. Lab Invest. 1990;63:144–161
- Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest. 1998;102:538–549
- Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodeling interface in human cirrhosis. Hepatology. 1999;29:1768–1778
- . Cell surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells. Proc Natl Acad Sci U S A. 1988;85:3110–3114
- Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers. Int J Cancer. 1997;71:383–389
- Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin. Cancer Res. 1993;53:3327–3335
- Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection. J Biol Chem. 1998;273:7222–7227
- Natural substrates of dipeptidyl peptidase IV. Adv Exp Med Biol. 2000;477:67–87
- . A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melanocytic cells. J Exp Med. 1999;190:311–322
- Regulation of fibroblast migration on collagenous matrix by a cell surface peptidase complex. J Biol Chem. 2002;277:29231–29241
- . Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor alpha. Am J Respir Crit Care Med. 1995;152:2163–2169
- . TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study. Am J Respir Cell Mol Biol. 1996;14:131–138
- . Epithelial cell–fibroblast interactions in lung injury and repair. Am J Pathol. 1990;137:385–392
- Fibroblasts isolated after fibrotic lung injury induce apoptosis of alveolar epithelial cells in vitro. Am J Physiol. 1995;269:L819–L828
- . Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP). J Clin Pathol. 2001;54:132–138
- . PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism. Cancer Res. 2004;64:5471–5480
- . Fibroblast heterogeneity in physiological conditions and fibrotic disease. Springer Semin Immunopathol. 1999;21:385–395
- The thyroid hormone–induced tail resorption program during Xenopus laevis metamorphosis. Proc Natl Acad Sci U S A. 1996;93:1924–1929
- . Transforming growth factor β. In: Clark RAF editors. The molecular cell biology of wound repair. New York: Plenum Press; 1996;p. 275–308
- . Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching. Am J Pathol. 2003;162:533–546
☆ This study was supported by PHS grant P50-HL67663 and the Commonwealth Universal Research Enhancement Program, Pennsylvania Department of Health.
PII: S0046-8177(05)00690-8
doi: 10.1016/j.humpath.2005.11.020
© 2006 Elsevier Inc. All rights reserved.
« Previous
Next »
Human Pathology
Volume 37, Issue 3
, Pages 352-360
, March 2006
