Human Pathology
Volume 40, Issue 7 , Pages 918-923 , July 2009

Recommendations for the reporting of surgically resected thymic epithelial tumors

  • Jamie A. Weydert, MD

      Affiliations

    • Department of Pathology, The University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    • Corresponding Author InformationCorresponding author. 5239C RCP, Department of Pathology, 200 Hawkins Drive, Iowa City IA 52242, USA.
    • ,
  • Barry R. De Young, MD

      Affiliations

    • Department of Pathology, The University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    • ,
  • Kevin O. Leslie, MD

      Affiliations

    • Department of Pathology, The Mayo Clinic Arizona, Scottsdale, AZ 85259, USA
    • ,
  • Prepared on behalf of the Association of Directors of Anatomic and Surgical Pathology

Received 26 February 2009 ,Accepted 3 March 2009.

References 

  1. In:  Travis WD,  Brambilla E,  Muller-Hermelink HK,  Harris CC editor. World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of the Lung, Pleura, Thymus, and Heart. Lyon: IARC Press; 2004;p. 145–195
  2. Suster S, Moran C. Thymoma, atypical thymoma, and thymic carcinoma: a novel conceptual approach to the classification of neoplasms of thymic epithelium. Am J Clin Pathol. 1999;111:826–833
  3. Marino M, Muller-Hermelink HK. Thymoma and thymic carcinoma: relation of thymoma epithelial cells to the cortical and medullary differentiation of the thymus. Virchows Arch. 1985;407:119–149
  4. Bernatz PE, Harrison EG, Claggett OT. Thymoma: a clinicopathologic study. J Thorac Cardiovasc Surg. 1961;42:424–444
  5. Masaoka A, Monden Y, Nakahara K, Tanioka T. Follow-up study of thymomas with special reference to their clinical stages. Cancer. 1981;48:2485–2492
  6. Koga K, Matsuno Y, Noguchi M, et al. A review of 79 thymomas: modification of staging system and reappraisal of conventional division into invasive and non-invasive thymoma. Pathol Int. 1994;44:359–367
  7. Wright CD, Wain JC, Wong DR, et al. Predictors of recurrence in thymic tumors: Importance of invasion, World Health Organization histology, and size. J Thorac Cardiovasc Surg. 2005;130:1413–1421
  8. Singhal S, Shrager JB, Rosenthal DI, LiVolsi VA, Kaiser LR. Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation. Ann Thorac Surg. 2003;76:1635–1642
  9. Rena O, Papalia E, Oliaro A, et al. Does adjuvant radiation therapy improve disease-free survival in completely resected Masaoka stage II thymoma?. Eur J Cardiothorac Surg. 2007;31:109–113
  10. Moran CA, Suster S. On the histologic heterogeneity of thymic epithelial neoplasms: impact of sampling in subtyping and classification of thymomas. Am J Clin Pathol. 2000;114:760–766
  11. Juttner FM, Fellbaum C, Popper H, Arian K, Pinter H, Friehs G. Pitfalls in intraoperative frozen section histology of mediastinal neoplasms. Eur J Cardiothorac Surg. 1990;4:584–586
  12. Kornstein MJ, Max LD, Wakely PE. Touch imprints in the intraoperative diagnosis of anterior mediastinal neoplasms. Arch Pathol Lab Med. 1996;120:1116–1122
  13. Chen G, Marx A, Wen-Hu C, et al. New WHO histologic classification predicts prognosis of thymic epithelial tumors. Cancer. 2002;95:420–429
  14. Lardinois D, Rechsteiner R, Lang RH, et al. Prognostic relevance of Masaoka and Muller-Hermelink classification in patients with thymic tumors. Ann Thorac Surg. 2000;69:1550–1555
  15. Rieker RJ, Hoegel J, Morresi-Hauf A, et al. Histologic classification of thymic epithelial tumors: comparison of established classification schemes. Int J Cancer. 2002;98:900–906
  16. Pomplun S, Wotherspoon AC, Shah G, Goldstraw P, Ladas G, Nicholson AG. Immunohistochemical markers in the differentiation of thymic and pulmonary neoplasms. Histopathology. 2002;40:152–158
  17. Pan CC, Chen PCH, Chiang H. KIT (CD117) is frequently overexpressed in thymic carcinomas but is absent in thymomas. J Pathol. 2004;202:375–381
  18. Suster S. Thymic carcinoma: update of current diagnostic criteria and histologic types. Semin Diagn Pathol. 2005;22:198–212

PII: S0046-8177(09)00094-X

doi: 10.1016/j.humpath.2009.03.012

Human Pathology
Volume 40, Issue 7 , Pages 918-923 , July 2009

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