Human Pathology
Volume 40, Issue 9 , Pages 1213-1223, September 2009

Ovarian carcinoma pathology and genetics: recent advances

  • C. Blake Gilks, MD

      Affiliations

    • Department of Pathology, Vancouver General Hospital and University of British Columbia, Vancouver BC, Canada V5Z 1M9
    • Corresponding Author InformationCorresponding author.
  • ,
  • Jaime Prat, MD

      Affiliations

    • Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Spain, 08025

Received 24 February 2009; received in revised form 7 April 2009; accepted 8 April 2009. published online 25 June 2009.

Summary 

In this review we summarize recent advances in the histopathological diagnostic criteria and molecular pathology of the main subtypes of ovarian surface epithelial carcinoma. These advances have greatly improved our understanding of the biology of ovarian carcinoma and are also relevant to patient management. With progress toward subtype-specific treatment of ovarian carcinoma, accurate, reproducible histopathological diagnosis of these subtypes by practicing pathologists is increasingly important.

Keywords: Ovarian cancer, Ovarian surface epithelial carcinoma, Tumor cell type, Serous, Clear cell, Endometrioid, Mucinous

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PII: S0046-8177(09)00140-3

doi:10.1016/j.humpath.2009.04.017

Human Pathology
Volume 40, Issue 9 , Pages 1213-1223, September 2009