Human Pathology
Volume 40, Issue 12 , Pages 1774-1782, December 2009

Large cell change of hepatocytes in chronic viral hepatitis represents a senescent-related lesion

  • Hiroko Ikeda

      Affiliations

    • Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa 920-8640, Japan
    • Molecular Cellular Pathology, Kanazawa University Graduate School of Medicine, Kanazawa 920-8640, Japan
  • ,
  • Motoko Sasaki

      Affiliations

    • Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa 920-8640, Japan
  • ,
  • Yasunori Sato

      Affiliations

    • Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa 920-8640, Japan
  • ,
  • Kenichi Harada

      Affiliations

    • Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa 920-8640, Japan
  • ,
  • Yoh Zen

      Affiliations

    • Section of Diagnostic Pathology, Kanazawa University Hospital, Kanazawa 920-8620, Japan
  • ,
  • Takeshi Mitsui

      Affiliations

    • Department of Surgery, Fukui Saiseikai Hospital, Fukui 918-8503, Japan
  • ,
  • Yasuni Nakanuma

      Affiliations

    • Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa 920-8640, Japan
    • Corresponding Author InformationCorresponding author.

Received 4 February 2009; received in revised form 3 June 2009; accepted 11 June 2009. published online 07 September 2009.

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PII: S0046-8177(09)00224-X

doi:10.1016/j.humpath.2009.06.009

Human Pathology
Volume 40, Issue 12 , Pages 1774-1782, December 2009