Human Pathology
Volume 41, Issue 2 , Pages 262-270, February 2010

p53 expression in tumor-stromal fibroblasts is closely associated with the nodal metastasis and outcome of patients with invasive ductal carcinoma who received neoadjuvant therapy

  • Takahiro Hasebe, MD, PhD

      Affiliations

    • Clinical Trials and Practice Support Division, Pathology Consultation Service, Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104-0045, Japan
    • Corresponding Author InformationCorresponding author.
  • ,
  • Nobuko Tamura, MD

      Affiliations

    • Department of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Nao Okada, MD

      Affiliations

    • Department of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Takashi Hojo, MD

      Affiliations

    • Department of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Sadako Akashi-Tanaka, MD, PhD

      Affiliations

    • Department of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Chikako Shimizu, MD

      Affiliations

    • Division of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Histoshi Tsuda, MD, PhD

      Affiliations

    • Clinical Laboratory Division, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Tatsuhiro Shibata, MD, PhD

      Affiliations

    • Cancer Genomics Project, National Cancer Center Research Institute, Tokyo 104-0045, Japan
  • ,
  • Yuko Sasajima, MD, PhD

      Affiliations

    • Clinical Laboratory Division, National Cancer Center Hospital, Tokyo 104-0045, Japan
  • ,
  • Motoki Iwasaki, MD, PhD

      Affiliations

    • Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo 104-0045, Japan
  • ,
  • Takayuki Kinoshita, MD, PhD

      Affiliations

    • Department of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan

Received 10 April 2009; received in revised form 27 July 2009; accepted 30 July 2009. published online 16 October 2009.

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 This study was supported in part by a Grant-in-Aid for Scientific Research (KAKENHI) (C) (19590378, 21590393) from Japan Society for the Promotion of Science and in part by a Grant-in-Aid for Cancer Research from the Ministry of Health, Labor and Welfare (20-16) of Japan.

PII: S0046-8177(09)00284-6

doi:10.1016/j.humpath.2009.07.021

Human Pathology
Volume 41, Issue 2 , Pages 262-270, February 2010