Human Pathology
Volume 41, Issue 1 , Pages 145-149, January 2010

Infiltrating glomus tumor of uncertain malignant potential arising in the kidney

  • Jespal Gill, MbChb

      Affiliations

    • Diagnostic Medlab, Surgical Pathology, Auckland, 1060 New Zealand
    • Corresponding Author InformationCorresponding author.
  • ,
  • Christiaan Van Vliet, MbChb

      Affiliations

    • Labplus, Auckland City Hospital, Grafton, Auckland, 1010 New Zealand

Received 20 February 2009; received in revised form 7 August 2009; accepted 7 August 2009. published online 09 November 2009.

Summary 

Glomus tumors closely resemble the normal glomus body and have a predilection for skin and subcutaneous tissue. These tumors rarely present in visceral organs. We report a case involving the kidney. This glomus tumor displays typical cytology and immunohistochemical profile of glomus tumors elsewhere. However, this tumor is large, has a deep location and exhibits an infiltrative margin and increased mitotic activity. These features, by current definition, would suggest malignant behavior. However, the rarity of such an entity in the kidney highlights the need for caution and a diagnosis in a continuum between benignity and malignancy. To the best of our knowledge, this report is the first case of infiltrating glomus tumor or glomus tumor of uncertain malignant potential arising in the kidney.

Keywords: Kidney, Mesenchymal tumor, Glomus tumor, Glomangioma, Glomangiomyoma, Malignant, Glomus tumor, Glomus tumor of uncertain malignant potential, Infiltrating glomus tumor

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PII: S0046-8177(09)00287-1

doi:10.1016/j.humpath.2009.08.003

Human Pathology
Volume 41, Issue 1 , Pages 145-149, January 2010