Human Pathology
Volume 41, Issue 2 , Pages 286-292 , February 2010

t(8;21)(q22;q22) Translocation involving AML1 and ETO in B lymophoblastic leukemia

  • Huan-You Wang, MD, PhD

      Affiliations

    • Division of Hematopathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9073, USA
    • Corresponding Author InformationCorresponding author. Department of Pathology, UCSD School of Medicine, La Jolla, CA 92093-0987, USA.
    • ,
  • Carlos A. Tirado, PhD

      Affiliations

    • Division of Cytogenetics, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9073, USA

Received 9 July 2009 ,Revised 4 August 2009 ,Accepted 7 August 2009.

References 

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  14. Bacher U, Schnittger S, Gruneisen A, Haferlach T, Kern W, Haferlach C. Inverted duplication dup(1)(q32q21) as sole aberration in lymphoid and myeloid malignancies. Cancer Genet Cytogenet. 2009;188:108–111
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  16. Dicker F, Haferlach C, Kern W, Haferlach T, Schnittger S. Trisomy 13 is strongly associated with AML1/RUNX1 mutations and increased FLT3 expression in acute myeloid leukemia. Blood. 2007;110:1308–1316
  17. Kuchenbauer F, Schnittger S, Look T, et al. Identification of additional cytogenetic and molecular genetic abnormalities in acute myeloid leukemia with t(8;21)/AML-ETO. Br J Heamatol. 2006;134:616–619
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PII: S0046-8177(09)00289-5

doi: 10.1016/j.humpath.2009.08.004

Human Pathology
Volume 41, Issue 2 , Pages 286-292 , February 2010

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