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Human Pathology
Volume 41, Issue 3
, Pages 366-374
, March 2010
Lymphatic and blood vessels in scleroderma skin, a morphometric analysis
References
- . The pathology of scleroderma vascular disease. Rheum Dis Clin North Am. 2008;34:41–55
- . Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest. 2007;117:557–567
- . Endothelial and fibroblastic activation in scleroderma. The myth of the “uninvolved skin”. Arthritis Rheum. 1991;34:1495–1501
- . Systemic sclerosis. A vascular perspective. Rheum Dis Clin North Am. 1996;22:675–694
- . How does endothelial cell injury start? The role of endothelin in systemic sclerosis. Arthritis Res Ther. 2007;9:S2
- . Early detection of connective tissue disease in patients with Raynaud's phenomenon. Rheum Dis Clin North Am. 1990;16:11–30
- Nailfold videocapillaroscopic patterns and serum autoantibodies in systemic sclerosis. Rheumatology. 2004;43:719–726
- Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circ Res. 2004;95:109–116
- Elevated vascular endothelial growth factor in Systemic Sclerosis. J Rheumatol. 2003;30:1529–1533
- Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers. Arthritis Res. 2002;4:R11
- Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J. 2002;21:1939–1947
- . Assessment of vascular involvement. Clin Exp Rheumatol. 2003;21:S9–S14
- . New insights into the molecular control of the lymphatic vascular system and its role in disease. J Invest Dermatol. 2006;126:2167–2177
- Radiogenic lymphangiogenesis in the skin. Am J Pathol. 2007;171:338–348
- . Reduction of lymphatic vessels in photodamaged human skin. J Dermatol Sci. 2007;47:241–243
- . new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest. 2002;82:1255–1257
- . Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005;166:913–921
- Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood. 2004;104:1048–1057
- . Expression of VEGFR-3 and 5′-Nase in regenerating lymphatic vessels of the cutaneous wound healing. Microsc Res Tech. 2004;64:279–286
- Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis. Blood. 2008;111:4571–4579
- TGF-beta1 is a negative regulator of lymphatic regeneration during wound repair. Am J Physiol Heart Circ Physiol. 2008;295:H2113–H2127
- Lymphatic microangiopathy of the skin in systemic sclerosis. Rheumatology (Oxford). 1999;38:221–227
- Scleroderma (systemic sclerosis) classification, subsets and pathogenesis. J Rheumatol. 1988;15:202–205
- In: West BT, Welch BT, Gatecki AT editor. Linear mixed models. A practical guide using statistical software. Boca Raton (Fla): Chapman and Hall/CRC; 2007;p. 353
- . The ageing of the blood supply and the lymphatic drainage of the skin. Micron. 2004;35:161–171
- . Cutaneous histiocytic lymphangitis: an unusual manifestation of rheumatoid arthritis. Australas J Dermatol. 2000;41:101–105
- . Intravascular or intralymphatic histiocytosis associated with rheumatoid arthritis: a report of 4 cases. J Am Acad Dermatol. 2004;50:585–590
- Protein-losing enteropathy in systemic lupus erythematosus. Rev Hosp Clin Fac Med Sao Paulo. 1991;46:34–37
- Variation of neuronal nitric oxide synthase in systemic sclerosis skin. Arthritis Rheum. 2006;54:202–213
- Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?. PLoS ONE. 2008;e1452:3
- . Vascular disease in scleroderma: mechanisms of vascular injury. Rheum Dis Clin North Am. 2008;34:57–71
- . Vascular disease in scleroderma: angiogenesis and vascular repair. Rheum Dis Clin North Am. 2008;34:73–79
- . Defective vasculogenesis in systemic sclerosis. Lancet. 2004;364:603–610
- Bone marrow endothelial progenitors are defective in systemic sclerosis. Arthritis Rheum. 2006;54:2605–2615
- . Circulating progenitor cells and scleroderma. Curr Rheumatol Rep. 2008;10:183–188
- . Structure and functions of lymphatics. J Invest Dermatol. 1989;93:18S–24S
- . Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol. 2007;8:464–478
- . High circulating levels of VEGF-C suggest abnormal lymphangiogenesis in systemic sclerosis. Rheumatology (Oxford). 2008;47:1727–1728
- Increased but imbalanced expression of VEGF and its receptors has no positive effect on angiogenesis in systemic sclerosis skin. Clin Exp Rheumatol. 2002;20:641–646
- Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res. 1999;85:221–228
- Presence of bone marrow-derived circulating progenitor endothelial cells in the newly formed lymphatic vessels. Blood. 2005;106:4184–4190
This work was supported by PAR grants of the University of Siena, and the Arthritis Research Campaign, UK.
PII: S0046-8177(09)00296-2
doi: 10.1016/j.humpath.2009.08.009
© 2010 Elsevier Inc. All rights reserved.
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Human Pathology
Volume 41, Issue 3
, Pages 366-374
, March 2010
