Human Pathology
Volume 41, Issue 3 , Pages 316-325 , March 2010

Clinically occult interstitial fibrosis in smokers: classification and significance of a surprisingly common finding in lobectomy specimens

  • Anna-Luise A. Katzenstein, MD

      Affiliations

    • Department of Pathology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    • Corresponding Author InformationCorresponding author.
    • ,
  • Sanjay Mukhopadhyay, MD

      Affiliations

    • Department of Pathology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    • ,
  • Conrado Zanardi, MD

      Affiliations

    • Department of Pathology, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    • ,
  • Elizabeth Dexter, MD

      Affiliations

    • Department of Surgery, SUNY Upstate Medical University, Syracuse, NY 13210, USA

Received 3 August 2009 ,Revised 3 September 2009 ,Accepted 9 September 2009.

References 

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  2. Auerbach O, Garfinkel L, Hammond EC. Relation of smoking and age to findings in lung parenchyma: a microscopic study. Chest. 1974;65:29–35
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  8. Hogg J, Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol Mech Dis. 2009;4:435–459
  9. Wright JL. Emphysema: concepts under change—a pathologist's perspective. Mod Pathol. 1995;8:873–880
  10. Cottin V, Nunes H, Brillet P-Y, et al. Combined pulmonary fibrosis and emphysema: a distinct underrecognized entity. Eur Respir J. 2005;26:586–593
  11. Grubstein A, Bendayan D, Schactman I, et al. Concomitant upper-lobe bullous emphysema, lower-lobe interstitial fibrosis and pulmonary hypertension in heavy smokers: report of eight cases and review of the literature. Respir Med. 2005;99:948–954
  12. Jankowich M, Polsky M, Klein M, Rounds S. Heterogeneity in combined pulmonary fibrosis and emphysema. Respiration. 2008;75:411–417
  13. Katzenstein A-LA, Mukhopadhyay S, Myers JL. Diagnosis of usual interstitial pneumonia and distinction from other fibrosing interstitial lung diseases. Hum Pathol. 2008;39:1275–1294

PII: S0046-8177(09)00331-1

doi: 10.1016/j.humpath.2009.09.003

Human Pathology
Volume 41, Issue 3 , Pages 316-325 , March 2010

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