Human Pathology
Volume 41, Issue 4 , Pages 614-615 , April 2010

Anaplastic lymphoma kinase 1 detected by immunohistochemistry in non–small cell lung cancer: a promising feature?

Received 12 August 2009 ,Accepted 16 November 2009.

References 

  1. Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non–small cell lung carcinomas. Hum Pathol. 2009;40:1152–1158
  2. Martelli MP, Sozzi G, Hernandez L, et al. EML4-ALK rearrangement in non–small cell lung cancer and non-tumor lung tissues. Am J Pathol. 2009;174:661–670
  3. Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res. 2009;15:3143–3149
  4. Chiarle R, Martinengo C, Mastini C, et al. The anaplastic lymphoma kinase is an effective oncoantigen for lymphoma vaccination. Nat Med. 2008;14:676–680
  5. Pulford K, Lamant L, Morris SW, et al. Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood. 1997;89:1394–1404

PII: S0046-8177(09)00427-4

doi: 10.1016/j.humpath.2009.11.009

Human Pathology
Volume 41, Issue 4 , Pages 614-615 , April 2010

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