Human Pathology
Volume 41, Issue 5 , Pages 768-772 , May 2010

Ocular perivascular epithelioid cell tumor: report of 2 cases with distinct clinical presentations

  • Emiko Furusato, MD

      Affiliations

    • Department of Neuropathology and Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA
    • ,
  • J. Douglas Cameron, MD

      Affiliations

    • Department of Neuropathology and Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA
    • ,
  • Roger W. Newsom, MD

      Affiliations

    • Tidewater Eye Centers, Portsmouth, VA 23707, USA
    • ,
  • Takashi Fujishiro, MD

      Affiliations

    • Department of Ophthalmology, Saitama Red Cross Hospital, 338-8553, Japan
    • ,
  • Takayoshi Kojima, MD, PhD

      Affiliations

    • Department of Ophthalmology, Saitama Red Cross Hospital, 338-8553, Japan
    • ,
  • Charles S. Specht, MD

      Affiliations

    • Department of Pathology, Ophthalmology, and Neurosurgery, Penn State Hershey, Hershey, PA 17033, USA
    • ,
  • John F. Fetsch, MD

      Affiliations

    • Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA
    • ,
  • Bungo Furusato, MD

      Affiliations

    • Department of Genitourinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA
    • ,
  • Isabell A. Sesterhenn, MD

      Affiliations

    • Department of Genitourinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA
    • ,
  • Elisabeth J. Rushing, MD

      Affiliations

    • Department of Neuropathology and Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA
    • Corresponding Author InformationCorresponding author.

Received 20 October 2009 ,Revised 17 December 2009 ,Accepted 18 December 2009.

References 

  1. Martignoni G, Pea M, Reghellin D, Zamboni G, Bonetti F. PEComas: the past, the present and the future. Virchows Arch. 2008;452:119–132
  2. Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature. Am J Surg Pathol. 2005;29:1558–1575
  3. Iyengar P, Deangelis DD, Greenberg M, Taylor G. Perivascular epithelioid cell tumor of the orbit: a case report and review of the literature. Pediatr Dev Pathol. 2005;8:98–104
  4. Guthoff R, Guthoff T, Mueller-Hermelink HK, Sold-Darseff J, Geissinger E. Perivascular epithelioid cell tumor of the orbit. Arch Ophthalmol. 2008;126:1009–1011
  5. Shields JA, Eagle RC, Shields CL, De Potter P. Acquired neoplasms of the nonpigmented ciliary epithelium (adenoma and adenocarcinoma). Ophthalmology. 1996;103:2007–2016
  6. Zimmerman LE, Fine BS. Production of hyaluronic acid by cysts and tumors of the ciliary body. Arch Ophthalmol. 1964;72:365–379
  7. Font RL, Jurco S, Zimmerman LE. Alveolar soft-part sarcoma of the orbit: a clinicopathologic analysis of seventeen cases and a review of the literature. Hum Pathol. 1982;13:569–579
  8. Argani P, Lal P, Hutchinson B, Lui MY, Reuter VE, Ladanyi M. Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay. Am J Surg Pathol. 2003;27:750–761
  9. Tanaka M, Kato K, Gomi K, et al. Perivascular epithelioid cell tumor with SFPQ/PSF-TFE3 gene fusion in a patient with advanced neuroblastoma. Am J Surg Pathol. 2009;33:1416–1420

PII: S0046-8177(09)00457-2

doi: 10.1016/j.humpath.2009.12.006

Human Pathology
Volume 41, Issue 5 , Pages 768-772 , May 2010

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