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Masthead
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IFC
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Editorial Board
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Information for Authors
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ii
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Table of Contents
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iii-iv
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In This Issue
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v-vi
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| Current Topics |
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Author(s) |
Pages |
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Erythroid proliferations in myeloid neoplasms
12 December 2011
Summary: Prominent erythroid proliferations (in which erythroid elements comprise ≥50% of total bone marrow cells) can be seen in various hematopoietic stem cell neoplasms. The myeloproliferative neop...
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Sa A. Wang,
Robert P. Hasserjian
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153-164
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| Perspectives in Pathology |
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Author(s) |
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On being a pathologist—passing on the torch of knowledge
Ours was a family that valued education. My father, Herman Moe Roth, was an engineer and physicist. Before marriage, my mother, Blanche Brown, was a high school English teacher in Canadian, Oklahoma, ...
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Lawrence M. Roth
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165-171
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| Original Contributions |
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Author(s) |
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Fluorescence in situ hybridization mapping of esophagectomy specimens from patients with Barrett's esophagus with high-grade dysplasia or adenocarcinoma
05 August 2011
Summary: The progression of intestinal metaplasia to esophageal adenocarcinoma in patients with Barrett's esophagus is partly driven by chromosomal alterations that activate oncogenes and inactivate t...
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Shannon M. Brankley,
Emily G. Barr Fritcher,
Thomas C. Smyrk,
Matthew E. Keeney,
Michael B. Campion,
Jesse S. Voss,
Amy C. Clayton,
Kenneth K. Wang,
Lori S. Lutzke,
Benjamin R. Kipp,
Kevin C. Halling
et al.
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172-179
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The CIC-DUX4 fusion transcript is present in a subgroup of pediatric primitive round cell sarcomas
03 August 2011
Summary: Pediatric undifferentiated soft tissue sarcomas are a group of diagnostically challenging tumors. Recent studies have identified a subgroup of undifferentiated soft tissue sarcomas with primi...
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Cassandra Graham,
Susan Chilton-MacNeill,
Maria Zielenska,
Gino R. Somers
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180-189
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Warty/basaloid penile intraepithelial neoplasia is more prevalent than differentiated penile intraepithelial neoplasia in nonendemic regions for penile cancer when compared with endemic areas: a comparative study between pathologic series from Paris and Paraguay
11 August 2011
Summary: Penile squamous cell carcinoma shows an ample geographic variation in its prevalence with regions of low (North America, Europe, Japan, and Israel) and high (Africa, Asia, and South America) ...
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Ana Soskin,
Anicke Vieillefond,
Agnes Carlotti,
Francoise Plantier,
Alcides Chaux,
Gustavo Ayala,
Elsa F. Velazquez,
Antonio L. Cubilla
et al.
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190-196
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Metallothionein expression in colorectal cancer: relevance of different isoforms for tumor progression and patient survival
05 August 2011
Summary: Metallothioneins are a family of small, cysteine-rich proteins with many functions. Immunohistochemical evaluation of all metallothionein 1 + 2 isoforms in colorectal tumors has demonstrated ...
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Juan Martín Arriaga,
Estrella Mariel Levy,
Alicia Inés Bravo,
Sergio Morales Bayo,
Mora Amat,
Mariana Aris,
Adrián Hannois,
Luisina Bruno,
María Paula Roberti,
Fernando Sánchez Loria,
Alejandro Pairola,
Eduardo Huertas,
José Mordoh,
Michele Bianchini
et al.
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197-208
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Folliculocentric B-cell–rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders
11 August 2011
Summary: We report three cases of follicular dendritic cell sarcoma (FDCS) showing a hitherto undescribed histological pattern consisting of nodular tumor growth associated with small B lymphocytes. F...
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Luisa Lorenzi,
Silvia Lonardi,
Giulia Petrilli,
Francesco Tanda,
Michelangelo Bella,
Licia Laurino,
Giuseppe Rossi,
Fabio Facchetti
et al.
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209-215
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Anal duct carcinoma: a report of 5 cases
05 August 2011
Summary: Anal duct carcinoma (ADC) is a rare lesion composed of glands undermining non-neoplastic squamous epithelium. We describe the clinicopathologic characteristics and follow-up of 5 cases of ADC...
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Zina Meriden,
Elizabeth A. Montgomery
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216-220
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Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer
05 August 2011
Summary: Cancer cells show a higher rate of anaerobic respiration than normal cells. The exact mechanisms for this higher glycolysis rate in cancer cells remain to be elucidated. The results of recent...
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Kyu Yeoun Won,
Sung-Jig Lim,
Gou Young Kim,
Youn Wha Kim,
Sang-Ah Han,
Jeong Yoon Song,
Dong-Ki Lee
et al.
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221-228
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Immunoreactivity to caspase-3, caspase-7, caspase-8, and caspase-9 forms is frequently lost in human prostate tumors
29 July 2011
Summary: Caspases are essential initiators and executioners of apoptosis. Changes in their expression may contribute to the development of proliferative disorders such as cancer, by altering the death...
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Gonzalo Rodríguez-Berriguete,
Laura Galvis,
Benito Fraile,
Fermín R de Bethencourt,
Pilar Martínez-Onsurbe,
Gabriel Olmedilla,
Ricardo Paniagua,
Mar Royuela
et al.
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229-237
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Dysplastic lesions in inflammatory bowel disease show increased positivity for the stem cell marker aldehyde dehydrogenase
05 August 2011
Summary: The chronic inflammatory state in patients with inflammatory bowel disease places them at a substantially elevated risk for developing colorectal carcinoma. Moreover, distinguishing an inflam...
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Adam D. Toll,
Bruce M. Boman,
Juan P. Palazzo
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238-242
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Vulvovaginal myofibroblastoma: expanding the morphological and immunohistochemical spectrum. A clinicopathologic study of 10 cases
05 August 2011
Summary: We analyzed the clinicopathologic features of 10 cases of vulvovaginal myofibroblastoma to widen its morphological and immunohistochemical spectrum. Most tumors (8/10 cases) were located in t...
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Gaetano Magro,
Rosario Caltabiano,
Denisa Kacerovská,
Giada Maria Vecchio,
Dmitry Kazakov,
Michal Michal
et al.
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243-253
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Characteristics of positive surgical margins in robotic-assisted radical prostatectomy, open retropubic radical prostatectomy, and laparoscopic radical prostatectomy: a comparative histopathologic study from a single academic center
05 August 2011
Summary: Studies detailing differences in positive surgical margin among open retropubic radical prostatectomy, laparoscopic radical prostatectomy, and robotic-assisted laparoscopic radical prostatect...
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Roula Albadine,
Matthew E. Hyndman,
Alcides Chaux,
J.Y. Jeong,
Shahrazad Saab,
Fabio Tavora,
Jonathan I. Epstein,
Mark L. Gonzalgo,
Christian P. Pavlovich,
George J. Netto
et al.
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254-260
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Sensitivity and specificity of finding of multinucleate trophoblastic giant cells in decidua in placentas from high-risk pregnancies
05 August 2011
Summary: This is a retrospective analysis of sensitivity and specificity of clustered placental basal plate multinucleate trophoblastic giant cells for various clinical conditions and placental lesion...
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Jerzy Stanek,
Jacek Biesiada
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261-268
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High CD10 expression predicts favorable outcome in surgically treated lymph node–positive bladder cancer patients
11 August 2011
Summary: CD10 predicts survival in different cancers. The prognostic significance in bladder cancer still has to be documented. One hundred fifty lymph node–positive bladder cancer patients were treat...
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Roland Seiler,
Michael von Gunten,
George N. Thalmann,
Achim Fleischmann
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269-275
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High nuclear protein kinase Cθ expression may correlate with disease recurrence and poor survival in oral squamous cell carcinoma
16 August 2011
Summary: Protein kinase Cs play important roles in many biological processes and tumorigenesis. This study examined the expression of protein kinase Cθ and assessed its significance in patients with o...
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Pei-Yi Chu,
Nicholas Chung-Heng Hsu,
Hui-Chun Tai,
Chung-Min Yeh,
Shu-Hui Lin,
Ming-Feng Hou,
Kun-Tu Yeh
et al.
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276-281
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Prognostic role of metastasis tumor antigen 1 in patients with ovarian cancer: a clinical study
11 August 2011
Summary: In this study, we investigated the prognostic value of metastasis tumor antigen 1 expression in 81 untreated patients with ovarian cancer. The expression of metastasis tumor antigen 1 was eva...
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Maria Grazia Prisco,
Gian Franco Zannoni,
Ilaria De Stefano,
Valerio Gaetano Vellone,
Lucia Tortorella,
Anna Fagotti,
Liliana Mereu,
Giovanni Scambia,
Daniela Gallo
et al.
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282-288
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| Case Studies |
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Author(s) |
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Tumor of the heart in a young woman; a rare manifestation of Wegener granulomatosis
01 August 2011
Summary: Wegener granulomatosis may rarely present with tumor masses that are in areas not typically involved by the disease. Although some cases have an associated positive anti-neutrophilic cytoplas...
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Remmi Singh,
Seymour Rosen
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289-292
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Cytogenetic and comparative genomic hybridization studies of an esophageal giant fibrovascular polyp: a case report
11 August 2011
Summary: Esophageal giant fibrovascular polyps are rare and are thought to represent redundant tumorlike or hamartomatous esophageal folds. Although most patients present with slowly evolving dysphagi...
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Zhongxin Yu,
Barbara L. Bane,
Ji-Yun Lee,
Jan V. Pitha,
Marvin Peyton,
John Houck,
Shibo Li
et al.
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293-298
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Ectomesenchymoma with t(1;12)(p32;p13) evolving from embryonal rhabdomyosarcoma shows no rearrangement of ETV6
01 August 2011
Summary: Ectomesenchymoma is a rare mesenchymal malignancy occurring mainly in the pediatric population. The hallmark diagnostic features are a combination of sarcoma, usually rhabdomyosarcoma (RMS) w...
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Sinead Howley,
Deirdre Stack,
Thomas Morris,
Michael McDermott,
Michael Capra,
David Betts,
Maureen J. O'Sullivan
et al.
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299-302
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Signet ring cell tumor of the minor salivary gland exhibiting benign behavior
03 August 2011
Summary: Signet ring cell (SRC) carcinomas are usually aggressive malignancies, arising most frequently in the stomach and gastrointestinal tract, but also, although less often, in other organs such a...
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Maria P. Foschini,
Chiara Baldovini,
Maria G. Pennesi,
Roberto Cocchi,
Roderick H.W. Simpson
et al.
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303-306
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Indeterminate cell tumor of the spleen
05 August 2011
Summary: Indeterminate cell tumor is an extremely rare neoplasm that mainly occurs in the skin. We report a case of indeterminate cell tumor arising from the spleen, a previously unreported site for i...
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Mingyi Chen,
Renuka Agrawal,
Niloofar Nasseri-Nik,
Andrew Sloman,
Lawrence M. Weiss
et al.
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307-311
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